Are you a curious scientist with experience in mass spectrometry and knowledge of a wide range of biochemical assay methods? Do you enjoy working hands-on in the lab in collaboration with a great team to push the boundaries of science? If yes, this is the position for you!

An exciting opportunity has arisen for a highly motivated Senior Scientist to join the Biochemical Assay Development team in the Assay, Profiling & Cell Sciences department within BioPharmaceuticals R&D, Discovery Sciences in Gothenburg, Sweden. This is a temporary position for 12 months with preferable starting date before 1st of July.


The Biochemical Assay Development team is responsible for the generation of novel biochemical and cellular assays to support projects in the early phases of the drug discovery pipeline. This is an opportunity for you to join the group as a lab-based scientist and be a key member of the team, developing biochemical assays for compound screening and mechanism-of-action studies in support of small molecule drug discovery projects.

We are looking for a candidate with experience around development of assays with the application of mass spectrometry in particular small molecules and peptides. Leading from the bench, you will apply your expertise and a passion for driving scientific questions, combined with strong team working ethics, to drug discovery projects.

What you will do:
In this role you will work as a lab-based scientist, delivering expertise in the area of biochemical
assay development; independently designing, developing and validating biochemical assays for
implementation in drug discovery projects, while incorporating the views of others. You will also
further develop our internal mass spectrometry capability with implementation on existing and
development of novel applications for screening and mechanism of action profiling.

We also want you to be an effective member of Drug Discovery Project Teams, contributing novel
ideas and using judgment and knowledge where appropriate to influence the work of the project.

Other responsibilities:

• To implement work-plans over agreed timelines such that the objectives of the project are met, including delivery of more than one agreed area of work in parallel where appropriate.
• To maintain an awareness of current developments in the literature and contribute to the continuous improvement process by identifying opportunities in the workplace where improvements can be made; may lead one or more aspects of scientific discipline within the team.

Essential in the role:

• Ph.D. in Biology, Pharmacology, Biochemistry or a related discipline or a MSc degree with significant relevant experience.
• Expertise in mass spectrometry, working with detection of enzymatic reactions.
• A practical understanding of a wide range of biochemical assay methods and technologies (not limited to mass spectrometry, for example fluorescence and luminescence techniques) as applied to a range of biological targets.
• Excellent problem-solving skills, good scientific judgement and communication skills.
• Excellent team working and networking skills with experience of interacting effectively across interfaces of discipline, culture, and expertise.

Desirable in the role:

• A practical understanding of assay optimisation, including statistical tools such as factorial experimental design, to enable generation of robust, reproducible and sensitive assays.
• Experience of working in external collaborations.

At AstraZeneca, we follow the science to explore and innovate. We are committed to treating, preventing, modifying and even curing some of the world's most complex diseases. Our team is driven by our desire to understand and reveal new insights. We are always learning from those living with diseases and harnessing digital, data science & AI to fast-forward our research. Join us as we push the boundaries of science to deliver life-changing medicines.